If you cross two affected individuals, and the offspring are unaffected, what type of inheritance is this?

Question

Autosomoal recessive, autosomal dominant, sex-linked recessive, sex-linked dominant? why yes or no for each.

Answer 1

Sorry Redbeard, gotta disagree here



If it was autosomal recessive, both affected parents would have to be homozygous to show it, so they could only produce homozygous recessive offspring, who would also be affected.

(or am I missing something??)



If it was autosomal dominant the parents could be Dd (affected), but could produce dd offspring who would be unaffected.



or it could be multifactorial

If you need enzyme A and enzyme B to complete a metabolic pathway, parent 1 with genotypes AAbb and parent 2 with the genotype aaBB would both be affected (unable to complete the metabolic pathway).

BUT, they could produce a AaBb offspring who would be unaffected.



John H

Answer 2

Autosomal recessive



Has to be recessive or offspring would have it

Has to be autosomal, since both parents had it